Long-term Aspect of Treatment with Metronidazole (Flagyl) in Trichomonal Vaginitis

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Long-term Aspect of Treatment with Metronidazole (flagyl) in Trichomonal Vaginitis.

The patients were seen at the V.D. Clinic of the Central Middlesex Hospital. Prostitutes and women known to be very promiscuous were excluded from the trial as it was thought that the re-infection rate might make the interpretation of results difficult. Flagyl (200 mg. three times daily for 10 days) and dummy tablets were dispensed in identical packets which were randomized and numbered. The ke...

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Nitrimidazine (Naxogin) compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis.

For more than 10 years very satisfactory results have been obtained in the treatment of trichomonal vaginitis using the standard 7-day course of metronidazole 200 mg. three times a day (Rodin, King, Nicol, and Barrow, 1960). In a recent trial it was shown that a 5-day course of 400 mg. twice daily produced equally satisfactory results, and was probably an easier regime from the patient's point ...

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Treatment of trichomonal vaginitis and urethritis and their complications with metronidazole ("Flagyl").

Both the literature and personal investigations (Popchristov, 1957) indicate beyond any doubt that the relative percentage of urethritis and vaginitis due to Trichomonas vaginalis rises with increased rates of non-gonococcal genital infections. Of 278 patients with non-gonococcal urethritis and colpitis, and 102 patients with gonorrhoea seen at the Dispensary of the Institute for Skin and Vener...

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Nifuratel compared with metronidazole in the treatment of trichomonal vaginitis.

Nifuratel (Magmilor) was compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis by a randomized double-blind trial. Only 18 out of 47 patients (38%) treated with nifuratel were found to be cured, whereas 42 out of 49 patients (85%) treated with metronidazole were cured. Severe reactions, necessitating withdrawal of treatment, occurred in three patients treated with nifur...

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Managing trichomonal vaginitis refractory to conventional treatment with metronidazole.

Three patients with vulvovaginitis caused by Trichomonas vaginalis, which was refractory to conventional treatment with metronidazole are described. The T vaginalis strain isolated from one patient was resistant to metronidazole (minimum inhibitory concentration (MIC) more than 100 mg/l) under aerobic conditions, although under anaerobic conditions it was as susceptible as a normal reference st...

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ژورنال

عنوان ژورنال: Sexually Transmitted Infections

سال: 1963

ISSN: 1368-4973

DOI: 10.1136/sti.39.4.258